Palladium-catalyzed S-benzylation of unprotected mercaptobenzoic acid with benzyl alcohols in water.
نویسندگان
چکیده
Palladium-catalyzed S-benzylation of unprotected mercaptobenzoic acids with benzyl alcohols gave only S-benzylated mercaptobenzoic acids in good yields. Water may play an important role for the smooth generation of the (η(3)-benzyl)palladium species by activation of the hydroxyl group of the benzyl alcohol.
منابع مشابه
Mercaptobenzoic acid-palladium(0) complexes as active catalysts for S-benzylation with benzylic alcohols via (η(3)-benzyl)palladium(II) cations in water.
Mercaptobenzoic acid-palladium(0) complexes show high catalytic activity for S-benzylation with benzylic alcohols via the (η(3)-benzyl)palladium(II) cation in water. Notably, these palladium(0) complexes could play an important role in formation of active (η(3)-benzyl)palladium(II) cation complexes followed by S-benzylation. Hammett studies on the rate constants of S-benzylation by various subs...
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ورودعنوان ژورنال:
- Organic & biomolecular chemistry
دوره 10 15 شماره
صفحات -
تاریخ انتشار 2012